An allocation problem is a type of aggregation problem in which the values of individuals' opinions on some set of variables (canonically a set of mutually exclusive and exhaustive possibilities) sum to a constant. This paper shows that for realistic allocation problems, namely ones in which the set of possible opinion values is finite, the only universal aggregation methods that satisfy two commonly invoked conditions are the dictatorial ones. The two conditions are, first, that the aggregate opinion on any variable (...) depends only on the individuals' opinions on that variable and not on their opinions on any other variable and, secondly, that the aggregate opinion minimally preserves unanimous individual opinion. Connections between this result and similar ones in the literature on judgment aggregation are explored and their significance assessed. (shrink)

IntroductionTranscranial magnetic stimulation is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation is a modification of TMS with similar efficacy and shorter session duration. The geriatric population has many comorbidities and a high prevalence of depression, but few clinical trials are conducted specifically for this age group. TBS could be an option in this population, offering the advantages of few side effects and no pharmacological interactions. Therefore, our aim is to investigate the (...) efficacy of TBS in geriatric depression.Clinical trial registration[https://clinicaltrials.gov/ct2/], identifier [NCT04842929]. (shrink)

It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...) doing so would violate some people's moral commitments regarding human embryos? Robust stakeholder engagement preceded adoption of the fourteen‐day limit and should arguably be part of efforts to reassess it. Such engagement could also consider the need for enhanced oversight of human embryo research. In the meantime, developing and implementing reliable oversight systems should help foster high‐quality research and public confidence in it. (shrink)

BackgroundThe outbreak of novel coronavirus disease 2019 has caused a global panic and public concern due to its mortality ratio and lack of treatments/vaccines. Reduced levels of physical activity have been reported during the outbreak, affecting the normal daily pattern.ObjectiveTo investigate the relationship of physical activity level with sleep quality and the effects of reduction physical activity levels on sleep quality.MethodsA Google form was used to address personal information, COVID-19 personal care, physical activity, and mental health of 1,907 adult volunteers. (...) Binary logistic regression was used to verify the association of physical activity parameters and sleep quality.ResultsInsufficient physical activity levels were a risk factor to have disturbed sleep pattern [OR: 1.28, 95% CI ]; however, when the BMI was added to the analysis, there was no more statistical difference [OR: 1.23, 95% CI ]. On the other hand, we found that the reduction of physical activity levels was associated with negative changes in sleep quality [OR: 1.73, 95% CI ], regardless all the confounders [OR: 1.30, 95% CI ], unless when feeling of depression was added in Model 6 [OR: 1.28, 95% CI ].ConclusionDisruption in daily physical activity routine, rather than physical activity level, negatively influences sleep quality during the COVID-19 quarantine. (shrink)

It now seems technically feasible to culture human embryos beyond the “fourteen‐day limit,” which has the potential to increase scientific understanding of human development and perhaps improve infertility treatments. The fourteen‐day limit was adopted as a compromise but subsequently has been considered an ethical line. Does it remain relevant in light of technological advances permitting embryo maturation beyond it? Should it be changed and, if so, how and why? What justifications would be necessary to expand the limit, particularly given that (...) doing so would violate some people's moral commitments regarding human embryos? Robust stakeholder engagement preceded adoption of the fourteen‐day limit and should arguably be part of efforts to reassess it. Such engagement could also consider the need for enhanced oversight of human embryo research. In the meantime, developing and implementing reliable oversight systems should help foster high‐quality research and public confidence in it. (shrink)

The aim of this study was to analyze the association between physical activity and eating habits during the COVID-19 pandemic among Brazilian adults. A sample of 1,929 participants answered an online survey, however 1,874 were included in the analysis. The impact of the COVID-19 pandemic on eating habits was assessed inquiring about participants' intake of fruits, vegetables, fried foods, and sweets during the pandemic. Physical activity was assessed by asking participants about their weekly frequency, intensity and number of minutes/hours engaging (...) in structured physical activities per week. Participants were then stratified into categories based on moderate-to-vigorous intensity and into active or inactive. Increased sweets consumption was the most commonly reported change to eating habits, followed by an increase in the consumption of vegetables, fruits, and fried foods. Physical activity practice was related to lower consumption of fried foods and sweets. A cluster analysis revealed subjects with higher the level of physical activity was more likely to follow a healthy diet. Thus, physical activity was positively associated with healthier eating habits. Health authorities must recommend regular physical as a strategy to improve overall health during the COVID-19 pandemic. Future studies should address the physical activity interventions to improve health status during a pandemic. (shrink)

In this essay an engineer and a philosopher, after many conversations, develop an argument for why the Aristotelian version of virtue ethics is the most promising way to develop what we call artificial moral, social agents, i.e. robots. This, evidently, applies to humans as well. There are several claims: first, that humans are not born moral, they are socialized into morality; second, that morality involves affect, emotion, feeling, before it engages reason; third, that how a moral being feels is related (...) to some narrative, whether moral or not; and finally, that narrativity is what builds a sense of a “moral” I, namely an authorial moral self. (shrink)

Dienes & Perner (D&P) argue that nondeclarative knowledge can take multiple forms. We provide empirical support for this from two related lines of research about the development of mathematical reasoning. We then describe how different forms of procedural and declarative knowledge can be effectively modeled in Anderson's ACT-R theory, contrasting this computational approach with D&P's logical approach. The computational approach suggests that the commonly observed developmental progression from more implicit to more explicit knowledge can be viewed as a consequence of (...) accumulating and strengthening mental representations. (shrink)

Peer review is a widely accepted instrument for raising the quality of science. Peer review limits the enormous unstructured influx of information and the sheer amount of dubious data, which in its absence would plunge science into chaos. In particular, peer review offers the benefit of eliminating papers that suffer from poor craftsmanship or methodological shortcomings, especially in the experimental sciences. However, we believe that peer review is not always appropriate for the evaluation of controversial hypothetical science. We argue that (...) the process of peer review can be prone to bias towards ideas that affirm the prior convictions of reviewers and against innovation and radical new ideas. Innovative hypotheses are thus highly vulnerable to being “filtered out” or made to accord with conventional wisdom by the peer review process. Consequently, having introduced peer review, the Elsevier journal Medical Hypotheses may be unable to continue its tradition as a radical journal allowing discussion of improbable or unconventional ideas. Hence we conclude by asking the publisher to consider re-introducing the system of editorial review to Medical Hypotheses. (shrink)

Prior knowledge structures (or schemas) confer multiple behavioral benefits. First, when we encounter information that fits with prior knowledge structures, this information is generally better learned and remembered. Second, prior knowledge can support prospective planning. In humans, memory enhancements related to prior knowledge have been suggested to be supported, in part, by computations in prefrontal and medial temporal lobe cortex. Moreover, animal studies further implicate a role for the hippocampus in schema-based facilitation and in the emergence of prospective planning signals (...) following new learning. To date, convergence across the schema-enhanced learning and memory literature may be constrained by the predominant use of hippocampally dependent spatial navigation paradigms in rodents, and non-spatial list-based learning paradigms in humans. Here, we targeted this missing link by examining the effects of prior knowledge on human navigational learning in a hippocampally dependent virtual navigation paradigm that closely relates to foundational studies in rodents. Outside the scanner, participants overlearned Old Paired Associates (OPA – item-location associations) in multiple spatial environments, and they subsequently learned New Paired Associates (NPA – new item-location associations) in the environments while undergoing fMRI. We hypothesized that greater OPA knowledge precision would positively affect NPA learning, and that the hippocampus would be instrumental in translating this new learning into prospective planning of navigational paths to NPA locations. Behavioral results revealed that OPA knowledge predicted one-shot learning of NPA locations, and neural results indicated that one-shot learning was predicted by the rapid emergence of performance-predictive prospective planning signals in hippocampus. Prospective memory relationships were not significant in parahippocampal cortex and were marginally dissociable from the primary hippocampal effect. Collectively, these results extend understanding of how schemas impact learning and performance, showing that the precision of prior spatial knowledge is important for future learning in humans, and that the hippocampus is involved in translating this knowledge into new goal-directed behaviors. (shrink)

ABSTRACT This paper proposes a vision of rhetoric as metaphysical enactment. This position contrasts with traditionally accepted views of rhetoric as phenomenological practice, evidenced prominently in contemporary rhetorical theory. I advance a framework that employs metaphorical accommodation and indicates a way that rhetoric can be situated as a perpetually productive force. The analytic tradition affords a method and vocabulary that when placed in conversation with rhetorical studies offers an alternative for viewing rhetoric as metaphysical enactment. I determine that rhetorical theory (...) should engage with rhetoric as a measure of action, activity, and vitality that raises our awareness and connects us. (shrink)

Spatial asymmetries are an intriguing feature of directed attention. Recent observations indicate an influence of temperament upon the direction of these asymmetries. It is unknown whether this influence generalises to visual orienting behaviour. The aim of the current study was therefore to explore the relationship between temperament and measures of spatial orienting as a function of target hemifield. An exogenous cueing task was administered to 92 healthy participants. Temperament was assessed using Carver and White's (1994) Behavioural Inhibition System and Behavioural (...) Activation System (BIS/BAS) scales. Individuals with high sensitivity to punishment and low sensitivity to reward showed a leftward asymmetry of directed attention when there was no informative spatial cue provided. This asymmetry was not present when targets were preceded by spatial cues that were either valid or invalid. The findings support the notion that individual variations in temperament influence spatial asymmetries in visual orienting, but only when lateral targets are preceded by a non-directional (neutral) cue. The results are discussed in terms of hemispheric asymmetries and dopamine activity. (shrink)

Aesthetic emotions are elicited by different sensory impressions generated by music, visual arts, literature, theater, film, or nature scenes. Recently, the AESTHEMOS scale has been developed to facilitate the empirical assessment of such emotions. In this article we report a semantic profile analysis of aesthetic emotion terms that had been used for the development of this scale, using the GRID approach. This method consists of obtaining ratings of emotion terms on a set of meaning facets which represent five components of (...) the emotion process. The aims here were to determine the dimensionality of the GRID features when applied to aesthetic emotions and compare it to published results for emotion terms in general, and to examine the internal organization of the domain of aesthetic emotion terms in order to identify salient clusters of these items based on the similarity of their feature profiles on the GRID. Exploratory Principal Component Analyses suggest a four-dimensional structure of the semantic space consisting of valence, power, arousal, and novelty, converging with earlier GRID studies on large sets of standard emotion terms. Using cluster analyses, 15 clusters of aesthetic emotion terms with similar GRID feature profiles were identified, revealing the internal organization of the aesthetic emotion terms domain and meaningful subgroups of aesthetic emotions. While replication for further languages is required, these findings provide a solid basis for further research and methodological development in the realm of aesthetic emotions. (shrink)

BackgroundFreezing of gait is a disabling burden for Parkinson’s disease patients with poor response to conventional therapies. Combined deep brain stimulation of the subthalamic nucleus and substantia nigra moved into focus as a potential therapeutic option to treat the parkinsonian gait disorder and refractory FoG. The mechanisms of action of DBS within the cortical-subcortical-basal ganglia network on gait, particularly at the cortical level, remain unclear.MethodsTwelve patients with idiopathic PD and chronically-implanted DBS electrodes were assessed on their regular dopaminergic medication in (...) a standardized stepping in place paradigm. Patients executed the task with DBS switched off, conventional STN DBS and combined STN+SN DBS and were compared to healthy matched controls. Simultaneous high-density EEG and kinematic measurements were recorded during resting-state, effective stepping, and freezing episodes.ResultsClinically, STN+SN DBS was superior to conventional STN DBS in improving temporal stepping variability of the more affected leg. During resting-state and effective stepping, the cortical activity of PD patients in STIM OFF was characterized by excessive over-synchronization in the theta, alpha, and high-beta band compared to healthy controls. Both active DBS settings similarly decreased resting-state alpha power and reduced pathologically enhanced high-beta activity during resting-state and effective stepping compared to STIM OFF. Freezing episodes during STN DBS and STN+SN DBS showed spectrally and spatially distinct cortical activity patterns when compared to effective stepping. During STN DBS, FoG was associated with an increase in cortical alpha and low-beta activity over central cortical areas, while with STN+SN DBS, an increase in high-beta was prominent over more frontal areas.ConclusionsSTN+SN DBS improved temporal aspects of parkinsonian gait impairment compared to conventional STN DBS and differentially affected cortical oscillatory patterns during regular locomotion and freezing suggesting a potential modulatory effect on dysfunctional cortical-subcortical communication in PD. (shrink)

This paper presents an algorithm for analyzing social situations within a robot. We contribute a method that allows the robot to use information about the situation to select interactive behaviors. This work is based on interdependence theory, a social psychological theory of interaction and interpersonal situation analysis. Experiments demonstrate the utility of the information provided by the situation analysis algorithm and of the value of this method for guiding robot interaction. We conclude that the situation analysis algorithm offers a viable, (...) principled, and general approach to explore interactive robotics problems. (shrink)

In these highly selective and condensed considerations, I could only offer a comparison of the main sociological themes in Gurwitsch's inaugural dissertation with the corresponding themes in Schutz's first book. Other sociological themes were not discussed, mainly because they were not developed far enough in one or the other or both sources. The crucial theme of explicit and implicit ontological presuppositions had to be ignored because it demands an extensive treatment of its own. The same goes for the proper consideration (...) of the particular conceptions of Husserl mobilized by each author for his purposes.Even so, I hope to have conveyed an idea of the convergences and differences in the early views of Gurwitsch and Schutz, as mirrored in the studies which were compared. This article should be seen as a small beginning of the huge task of studying comprehensively the unique personal and intellectual friendship of two seminal thinkers and the influences they exercised upon each other's work, even though they operated in substantively quite different areas. (shrink)

This article investigates the challenge of developing a robot capable of determining if a social situation demands trust. Solving this challenge may allow a robot to react when a person over or under trusts the system. Prior work in this area has focused on understanding the factors that influence a person’s trust of a robot. In contrast, by using game-theoretic representations to frame the problem, we are able to develop a set of conditions for determining if an interactive situation demands (...) trust. In two separate experiments, human subjects were asked to evaluate either written narratives or mazes in terms of whether or not they require trust. The results indicate a _Φ_1= +0.592 and _Φ_2 = +0.406 correlation respectively between the subjects’ evaluations and the condition’s predictions. This is a strong correlation for a study involving human subjects. (shrink)

This article investigates the challenge of developing a robot capable of determining if a social situation demands trust. Solving this challenge may allow a robot to react when a person over or under trusts the system. Prior work in this area has focused on understanding the factors that influence a person’s trust of a robot (Hancock, et al., 2011). In contrast, by using game-theoretic representations to frame the problem, we are able to develop a set of conditions for determining if (...) an interactive situation demands trust. In two separate experiments, human subjects were asked to evaluate either written narratives or mazes in terms of whether or not they require trust. The results indicate aΦ1= +0.592 andΦ2= +0.406 correlation respectively between the subjects’ evaluations and the condition’s predictions. This is a strong correlation for a study involving human subjects. (shrink)

This article investigates the challenge of developing a robot capable of determining if a social situation demands trust. Solving this challenge may allow a robot to react when a person over or under trusts the system. Prior work in this area has focused on understanding the factors that influence a person’s trust of a robot (Hancock, et al., 2011). In contrast, by using game-theoretic representations to frame the problem, we are able to develop a set of conditions for determining if (...) an interactive situation demands trust. In two separate experiments, human subjects were asked to evaluate either written narratives or mazes in terms of whether or not they require trust. The results indicate aΦ1= +0.592 andΦ2= +0.406 correlation respectively between the subjects’ evaluations and the condition’s predictions. This is a strong correlation for a study involving human subjects. (shrink)

Background Regionalised models of health care delivery have important implications for people with disabilities and chronic illnesses yet the ethical issues surrounding disability and regionalisation have not yet been explored. Although there is ethics-related research into disability and chronic illness, studies of regionalisation experiences, and research directed at improving health systems for these patient populations, to our knowledge these streams of research have not been brought together. Using the Canadian province of Ontario as a case study, we address this gap (...) by examining the ethics of regionalisation and the implications for people with disabilities and chronic illnesses. The critical success factors we provide have broad applicability for guiding and/or evaluating new and existing regionalised health care strategies. Discussion Ontario is in the process of implementing fourteen Local Health Integration Networks (LHINs). The implementation of the LHINs provides a rare opportunity to address systematically the unmet diverse care needs of people with disabilities and chronic illnesses. The core of this paper provides a series of composite case vignettes illustrating integration opportunities relevant to these populations, namely: (i) rehabilitation and services for people with disabilities; (ii) chronic illness and cancer care; (iii) senior's health; (iv) community support services; (v) children's health; (vi) health promotion; and (vii) mental health and addiction services. For each vignette, we interpret the governing principles developed by the LHINs – equitable access based on patient need, preserving patient choice, responsiveness to local population health needs, shared accountability and patient-centred care – and describe how they apply. We then offer critical success factors to guide the LHINs in upholding these principles in response to the needs of people with disabilities and chronic illnesses. Summary This paper aims to bridge an important gap in the literature by examining the ethics of a new regionalisation strategy with a focus on the implications for people with disabilities and chronic illnesses across multiple sites of care. While Ontario is used as a case study to contextualize our discussion, the issues we identify, the ethical principles we apply, and the critical success factors we provide have broader applicability for guiding and evaluating the development of – or revisions to – a regionalised health care strategy. (shrink)

This introduction to the Common Knowledge symposium titled “Comparative Relativism” outlines a variety of intellectual contexts where placing the unlikely companion terms comparison and relativism in conjunction offers analytical purchase. If comparison, in the most general sense, involves the investigation of discrete contexts in order to elucidate their similarities and differences, then relativism, as a tendency, stance, or working method, usually involves the assumption that contexts exhibit, or may exhibit, radically different, incomparable, or incommensurable traits. Comparative studies are required to (...) treat their objects as alike, at least in some crucial respects; relativism indicates the limits of this practice. Jensen argues that this seeming paradox is productive, as he moves across contexts, from Lévi-Strauss's analysis of comparison as an anthropological method to Peter Galison's history of physics, and on to the anthropological, philosophical, and historical examples offered in symposium contributions by Barbara Herrnstein Smith, Eduardo Viveiros de Castro, Marilyn Strathern, and Isabelle Stengers. Comparative relativism is understood by some to imply that relativism comes in various kinds and that these have multiple uses, functions, and effects, varying widely in different personal, historical, and institutional contexts that can be compared and contrasted. Comparative relativism is taken by others to encourage a “comparison of comparisons,” in order to relativize what different peoples—say, Western academics and Amerindian shamans—compare things “for.” Jensen concludes that what is compared and relativized in this symposium are the methods of comparison and relativization themselves. He ventures that the contributors all hope that treating these terms in juxtaposition may allow for new configurations of inquiry. (shrink)

Comprehending the origin of marine invertebrate larvae remains a key domain of research for evolutionary biologists, including the repeated origin of direct developmental modes in echinoids. In order to address the latter question, we surveyed existing evidence on relationships of homology between the ectoderm territories of two closely related sea urchin species in the genus Heliocidaris that differ in their developmental mode. Additionally, we explored a recently articulated idea about homology called ‘organizational homology’ (Muller 2003. In: Muller GB, Newman SA, (...) editors. Origination of organismal form: beyond the gene in developmental and evolutionary biology. Cambridge, MA: A Bradford Book, The MIT Press. p 51–69. ) in the context of this specific empirical case study. Applying the perspective of organizational homology to our experimental system of congeneric echinoids has led us to a new hypothesis concerning the ectoderm evolution in these species. The extravestibular ectoderm of the direct developer Heliocidaris erythrogramma is a novel developmental territory that arose as a fusion of the oral and aboral ectoderm territories found in indirect developing echinoids such as Heliocidaris tuberculata. This hypothesis instantiates a theoretical principle concerning the origin of developmental modules, ‘integration’, which has been neglected because the opposite theoretical principle, ‘parcellation’, is more readily observable in events such as gene duplication and divergence (Wagner 1996. Am Zool 36:36–43). J. Exp. Zool. (Mol. Dev. Evol.) 306B:18– 34, 2006. (shrink)

Gyenis and Rédei (G&R) have shown that any prior _p_ on a finite algebra _A_, however chosen, significantly restricts the set of posteriors derivable from _p_ by Jeffrey conditioning (JC) on a nontrivial measurable partition (i.e., a partition consisting of members of _A_, at least one of which is not an atom of _A_). They support this claim by proving that the set of potential posteriors _not derivable_ from _p_ in this way, which they call the _Bayes blind spot of (...) p_, is large, having cardinality _c_ and normalized Lebesgue measure 1, as well as being of second Baire category for a natural metrizable topology. In the present paper, we establish results analogous to those of G&R for probability measures on any infinite sigma algebra of subsets of a countably infinite set (which requires distinctly different treatments of the topological and measure-theoretic cases). We also show, in both the finite and infinite cases, that all of the limitative results for a single prior _p_ continue to hold for the intersection of the Bayes blind spots of countably many priors. This leads us to reject the claim of G&R that the large size of blind spots in the single prior case is attributable to the limitations imposed by priors. We argue instead that it is the so-called _rigidity property_ of JC that accounts for the large size of Bayes blind spots. G&R also prove that _any_ potential posterior _q_ can be derived from a prior _p_ by at most two applications of JC on nontrivial partitions. But they remark that their particular two-stage derivation of an \(r \in BS(p)\) from _p_ is barely distinguishable from a single, complete reassessment on a trivial partition. We show, however, that there are two-stage derivations of _r_ from _p_ that require no direct assessment of the probability of any atom at either stage. Finally, in order to situate the aforementioned limitative results in the proper context, we demonstrate that a probability revision that would amount to complete reassessment within a Jeffrey evidentiary framework may arise, in a different evidentiary framework, in a way that involves no direct assessment of the probability of any atom, as, for example, in a generalization of Jeffrey’s solution to the problem of old evidence and new explanation. (shrink)

We define an $\mathfrak{R}$-group to be a stable group with the property that a generic element can only be algebraic over a generic. We then derive some corollaries for $\mathfrak{R}$-groups and fields, and prove a decomposition theorem and a field theorem. As a nonsuperstable example, we prove that small stable groups are $\mathfrak{R}$-groups.

We define an R-group to be a stable group with the property that a generic element (for any definable transitive group action) can only be algebraic over a generic. We then derive some corollaries for R-groups and fields, and prove a decomposition theorem and a field theorem. As a nonsuperstable example, we prove that small stable groups are R-groups.

This classic biography of Nietzsche, first published in the 1960s, was enthusiastically reviewed at the time. The biography is now reissued with its text updated in the light of recent research. Hollingdale's biography remains the single best account of the life and works for the student or non-specialist. The biography chronicles Nietzsche's intellectual evolution and discusses his friendship and breach with Wagner, his attitude towards Schopenhauer, and his indebtedness to Darwin and the Greeks. It follows the years of his (...) maturity and his mental collapse in 1889. The final part of the book considers the development of the Nietzsche legend during his years of madness. R. J. Hollingdale, one of the preeminent translators of Nietzsche, allows Nietzsche to speak for himself in a translation that transmits the vividness and virtuosity of Nietzsche's many styles. This is the ideal book for anyone interested in Nietzsche's life and work to learn why he is such a significant figure for the development of modern thought. (shrink)